Posted by bigcat on October 26, 2005, at 19:57:07
In reply to Dexedrine-OCD what about adding Clomipramine?, posted by Tom Twilight on October 26, 2005, at 9:45:13
> Hey Matt
>
Hey Tommy T.!> Sorry to hear your having such a horrible time with Dex
> Its a strange difficult med, sometimes I found it really helpful other times I found it hurtfull
>
> You haven't mentioned that you are taking any other meds with the Dex, so I'm going to assume your not on anything else.Actually, I'm currently on Nardil as well, and am considering some different combination/augmentation options which some insightful people on this board have suggested. I had a surprisingly great response to the Dex/Nardil combo a few months back (after YEARS of various trials which didn't provide any relief). When I went off it (long story), I didn't experience any withdrawal or crash surprisingly. For some reason, it was benign on my system. Since restarting the Dex (which I've tried a few times now) following this great remission, I've been SOOO hyperstimulated and compulsive, which hadn't occured nearly this severely when taking the Dex 6 months back.
>
> If this is the case then I would suggest you could try adding something to help with the OCD, rather than simply discontinueing the Dex
>
> (I should mention here that I don't suffer from OCD, although I did when I was a child, between 9-12, I still have some OCD characteristics like obsesive thought patterns)My history and current situation matches that entirely.
>> I found that Dex combined fairly well with Clomipramine.
> The two meds worked together fairly well, the Clomipramine worked great for anxiety (although not social anxiety) and sleep.
> Unfortunatly it also made me lethargic and fatigued
>
> Dexedrine counteracted the lethagy and fatigue, while the Clomiprame stopped me experiencing the anxiety I would normally experience with the Dex!> The combination also worked well for social anxiety.
>
> Infact the Clomipramine seemded to potentiate the Dex, perhapse because of its anti Colligenic affects.Very interesting. Something to consider, although the Dex muscle twitches, ticks, and overall physical discomfort are unbearable at this point (even at just 10mgs a day. When it gave me such a great AD effect, I was on 90mgs believe it or not, and didn't have these symptoms, or they were much milder and soon passed. So strange). I think I need to drop the Dex for now, and if I give it another trial in the future, I'll be armed with some combo strategies you suggested to combat this exhausting and totally out of control hyperstimulation (without an accompanying antidepressant or mental acuteness effect this time). I think the Anafrinal idea holds a great deal of promise for the future. I didn't mention that the Dex compulsiveness is paired with ridiculous obsessing (I get a song in my head and don't have a single thought for the rest of the day free from endlessly repeating the same verse in my head for hours on end. It truly is unbearable).
>
> Clomipramie has a lot of side effects, but you could try another OCD med like Fluvoxamine insteadThe Luvox gave me some start-up problems which made me drop it (exacerbated social phobia bordering on paranoia, debilitating self-consciousness/hypervigilance). I tried it recently after Serzone (which hadn't worked for me in the past) seemed to work very well initially and then quickly went in the other direction and brought the anxiety way up. (I guess these two drugs share some characteristics ??)
>
> Good luckGracias Amigo, I appreciate your thoughts and the valuable personal experience you shared... If I remember correctly, you were having difficulties getting a doc to prescribe you Marplan doses above 30mgs, which is totally ridiculous. Drop me an email (mlieb@wesleyan.edu) if you want to discuss this, as I've had some high-dose Marplan experience.
-matt-
poster:bigcat
thread:571695
URL: http://www.dr-bob.org/babble/20051024/msgs/572202.html