Posted by Jedi on September 3, 2005, at 2:23:31
In reply to Re: Most Effective Parnate Dosage for Social Phobi » willyee, posted by Chairman_MAO on August 30, 2005, at 10:18:47
> You really should give Nardil a try. One thing you could do is stay on Parnate and try LOW dosage Nardil (30-45 mg/day) simply for its GABAnergic effect, which will probably calm the overactivation of the Parnate somewhat.
> You could also try Nardil with wellbutrin, which I think I am going to try next time I see my dr.
Have you used Parnate with low dose Nardil? What kind of response did you get? I've tried Parnate for depression & anxiety with seroquel added, which mostly seemed to counteract the Parnate "high" for me. It just didn't work on my treatment resistant atypical depression. Now 90mg Nardil with 1mg clonazepam seems to give me about a 75 to 80 percent recovery to normal. But I am always struggling for that last 20 percent. I was on Wellbutrin SR with Nardil for some time and it seemed like a really good combination. Then my previous PDOC retired and I went to a major University Hospital to see supposedly one of the best PDOCs in the country for treatment resistant depression. Of course, he told me the combination was going to kill me and thought I should do ECT instead. Thanks a lot. I think I could probably present enough documentation to my current GP to let me try it again. The Wellbutrin seemed to help with a lot of the Nardil side effects but I remember it did seem to make me think a little slower. Another thought is going back to the Nardil with Nortriptyline. This combo worked pretty well and some research suggests that a MAOI with some tricyclics will help lessen the chance of a hypertensive crisis. Have you done any study on this? My other thought is to reduce my Nardil dose down to about 60mg and raise the clonazepam to 3mg per day. In theory this should lessen the Nardil side effects while raising the gaba even more to treat my social and generalized anxiety. Any thoughts on this combination? Thanks for any advice you might have.