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Re: phase III anxiety trial for Ocinaplon's on hold

Posted by Tom Twilight on August 28, 2005, at 5:55:17

In reply to phase III anxiety trial for Ocinaplon's on hold, posted by aabag on August 25, 2005, at 23:14:38

> Just got the news, DOV's anxiolytic Ocinaplon was placed on hold, by the company, not the FDA.
The reason for the hold, a patient with elevated liver enzymes.
>
This is very frustrating, I'm suprised there hasn't been more of a reaction to this on babble
Unfortunatly after Viox drug companies are going to be extremely cautious about safety

In my opinion companiesare probably going to be overly cautious, lots of valuable medications like Nardil would never have seen the light of day with todays safety standards.

In answer to Linkadges question: Oncinaplon is supposed to have the anti anxiety effect of Benzo's without the potential for deppendence, or sedation.
It binds selectivly to the GABA A receptors responsible for anxiety, I think
I'm probably wrong!


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poster:Tom Twilight thread:546772
URL: http://www.dr-bob.org/babble/20050827/msgs/547504.html