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Re: Declan, that's exactly what I was thinking. .

Posted by med_empowered on August 21, 2005, at 14:39:24

In reply to Re: Declan, that's exactly what I was thinking. . » Sarah T., posted by AMD on August 21, 2005, at 14:25:09

Hey! I'm sorry about your troubles. Tricyclics have been used a good bit with helping post-cocain use depression. But...they can have all sorts of undesirable side effects, so you might want to back-burner that option for now. Provigil is a stimulant, technically a schedule IV w/ a bit of possibility of abuse. It seems to be pretty much non-addictive though, and it helps lots of people with tough-to-treat depression and narcolepsy and ADHD. I read somewhere that its being used in stimulant-withdrawal treatment...it boosts dopamine, but selectively, so there's less weight loss and blood pressure increase than with old school stimulants...its a good add-on to antidepressants for a lot of people. Wellbutrin would be an option...it mildly inhibits reuptake of dopamine, which could be helpful...as antidepressants go, its considered "cleaner" than a lot of the others for bipolar disorder, but you might get anxiety and weight loss. Aside from these, all I can think of (and this would be pretty hardcore, in terms of side effects) would be combining an MAOI (which will bump up the dopamine levels in your brain, but will also carry very strick dietary restrictions) with a Tricyclic (inhibits the reuptake of some chemicals in your brain, depending on the drug and dosage used) with a low-dose stimulant (Provigil, I think, can be used for this). This is the kind of combo used for "atypical" depression--depression characterized by lethargy, slow thoughts, lack of motivation, etc.--that fails to respond to "standard" treatment. Good luck!


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