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Re: About my post..and Suicide...

Posted by SLS on July 21, 2005, at 22:05:09

In reply to Re: About my post..and Suicide... SLS, posted by Jakeman on July 21, 2005, at 21:55:50

Hi Jake.

> > What sorts of things are you interested in discovering with long-term studies? Just curious.

> Efficacy. I remember when Prozac came out in the '80's with much fanfare..and shortly after it got much media attention including a picture of the capsule on the cover of Newsweek. There seemed to be an attitude that this was the magic pill. No one talked about whether or not its effect was lasting. As far as I know, Lilly has never admitted to the now widely reported poop-out phenomenon. And why should they? They didn't test the drug for long-term use.

You are exactly right. It would be nice to know at what rate poop-out occurs. One fact has become evident, though. Effexor does not poop-out as often as the SSRIs and brings more people to remission. I am still of the opinion that the TCAs poop out less often than SSRIs, and might even produce a more robust treatment response.

> My guess if that much of the back-lash against the psychiatric profession these days is partly due to the fact that people discover that these wonder drugs don't last.

I think there are several aspects to these drugs that leave them as being less than wonder drugs.

> I'm not against SSRI's or any other pharmacolgical approaches. I hope it's a start in the right direction that will bear more fruitful results in the future.

That's where I'm coming from.

> BTW, when is that segeline patch coming out? :-)

I am as clueless as you. Maybe early next year?

- Scott




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