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Re: Smart drug !! PS

Posted by rod on July 20, 2005, at 18:33:02

In reply to Re: Smart drug !! » linkadge, posted by rod on July 20, 2005, at 18:00:57

> > That is insane. It basically has the same actions as trileptal, and that was a dumb drug for me.
> >
> >
> > Linkadge
>
> ehrm no it isnt insane and only shares the common fact with Trileptal that it has an anticonvulsant effect.
>
> It worked for a few hours for me but then I crashed. Maybe the enzyme inducing effect it has. dont know for sure why.
>
> Other people reported the same about Dilantin (not the crash, though)
>
> But ok, I dont know much about its exact mechanism but I have once read it has a unique effect on modulating glutamate activity. No anticunvusive drug does it like Dilantin. No Na+ channel blockade or increasing gabaergic activity etc. like the other ones.... arrr I am too lazy to look it up. So regard this info with a grain of salt :D
>
> give it a try :)
>
> You are drug free, so *I* would do it in your position. Maybe you brain zaps will come to an end. well, who knows...
>
> nuff said
>
> bye
> Roland

Ok, I looked a little at pubmed. It seems its quite unclear how Dilantin works. Some suggest an effect on Sodium channels. anyway.

there is a interesting paper:

"Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15582833&query_hl=6

"... and phenytoin produced a modest but significant improvement in performance .."

good night
Roland


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URL: http://www.dr-bob.org/babble/20050718/msgs/530748.html