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Re: Lithium - is Seroquel necessary? » yesac

Posted by barbaracat on June 29, 2005, at 13:04:40

In reply to Re: Lithium - is Seroquel necessary?, posted by yesac on June 29, 2005, at 12:12:21

>
> I might try to take less Seroquel instead of less lithium. I need to talk to my psychiatrist to help me decide. One thing is that I think lithium augments Seroquel for me, and so it's like I need less Seroquel to get the same or even better benefits than when I was on it alone.
>
**That's what I suspect too. Lithium does seem so augment many meds. Not benzos for me, unfortunately, but I need less of everything else.

Obviously there's something going on with Seroquel that is helping you. Antipsychotics usually work their magic on schizoprenics by decreasing dopamine. Serotonin has an inverse effect on dopamine. I'm just scratching my head here, but increasing serotonin might be one way to do the same thing but without the histamine thing.

This morning I have first hand experience of that. I couldn't sleep last night and grabbed two of what I thought were temazepams from the cabinet. This morning could not rouse myself until the pee problem got critical and I'm still wobbling around forcing myself to not go back to bed. Looked at the pill bottle I'd left on the counter and it was doxepin, not temazepam! Dox is a heavy histamine hitter and every time I take one of those kinds of meds I feel out of it the whole day.

So, working with your pdoc you might be able to come up with something that can substitute the positive benefits.
>
> I'm thinking about it. Maybe Zoloft?

**Zoloft is a darn good AD. It was the only one I could tolerate for long periods of time and on high doses, even not being on lithium. So far I'm happy with Cymbalta at a micro dose, but if I were to switch it would be back to Zoloft.

>>I had a really bad experience with Prozac even when I was on lithium, so I doubt that I'd ever try that again.... plus, it makes me worry about any antidepressant, even though they're not all so activating.

**I understand. Sometimes I become convinced that once you start taking them, a permanent change occurs and you need them for life. But considering the dramatic change for the better I now feel after restarting a very small dose of an AD with lithium after years of being off, I know I need something.

When we're depressed we don't track right and worry about things that generally have solutions. It's usually when I'm not taking a med, or too little of the right one that I worry I'll need it forever. I worry about everything when I'm in an anxious depression. It's when I'm feeling good I usually have more enjoyable things to think about and my heart is filled with thanks for the little chemistry elves who make my pills. Good luck and hope you get the right combo. - Barbara


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poster:barbaracat thread:509665
URL: http://www.dr-bob.org/babble/20050627/msgs/521102.html