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Which dopaminergic drug to add ????

Posted by cache-monkey on June 26, 2005, at 18:04:42

Hey all,

It seems like I'm somewhat stable these days on Zyprexa (2.5 mg/day) and Klonopin (1.25 mg/day). This combo is taking care of some core set of dysthymic (leaning toward depression at times) and anxious symptoms. There's also possibly a very soft BP thrown in the mix. Anyway, I think it's really the Zyprexa more than anything that is doing much of the trick.

My p-doc and I want to add a dopaminergic drug to help out with a set of residual/drug-induced symptoms. In subjective order of importance these are:
* Dependence on cigarettes (every time I quit, I get depressed/anxious, even when using non-pharmacological aids)
* Slight sexual dysfunction from drug combo
* Residual ADD-like stuff and anhedonia
* Increase in appetite from the Zyprexa

My p-doc and I are looking at the following list of DA drugs:
* Amantadine
* Bromocriptine
* Mirapex
* Pergolide
* ReQuip
* low-dose Selegiline

At this point I'm leaning toward Bromocriptine or Selegiline due to some studies showing benefits for quitting smoking. Amantadine would probably round out the top three.

But, I would very much appreciate your input on these meds.

Thanks!
cache-monkey


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poster:cache-monkey thread:519410
URL: http://www.dr-bob.org/babble/20050622/msgs/519410.html