Posted by Elroy on June 19, 2005, at 20:42:24
In reply to Re: HPA Axis and Anti-Cortisol Therapy, posted by KaraS on June 19, 2005, at 17:58:53
24-hour Urinary Free Cortisol test gives an absolute as to your specifi daily totals. Blood cortisol tests are not good because you could be at a very low secretion point - or very high one - at the specific time that the blood is drawn.
The salivary tests - not the late night ones - but the generic ones - are better than the blood test IF you do the four times a day (every six hours) test. Still doesn't have the accuracy of the total 24-hr UFC for showing daily levels.
Also some people are "cyclical" Cushings so they might not actually over-secrete every day. Hence doing three spread out over 2 - 3 weeks.
If none are elevated then there's no reason to do the Late Night Salivary Cortisol tests. It is just primarily designed for separating out "real" Cushing's versus the Pseudo Cushing's cases...
> Hi Elroy,
> I just read that article the other day. Just a quick question: why do we need to take the three 24-hour UFC tests (that's Urinary Free Cortisol)? Can't we just get the salivary tests to begin with?