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Re: Trileptal 600mg - How much higher can I go? » SLS

Posted by Ron Hill on June 17, 2005, at 18:40:41

In reply to Re: Trileptal 600mg - How much higher can I go? » Ron Hill, posted by SLS on June 17, 2005, at 15:49:15

> I wish I had a better idea as to what is the average dosage used by people with bipolar disorder.

Scott,

I think that a dosage of 1200 mg/day for adults (or 1800 mg/day for kids) is about average for BP. This is consistent with woolav’s post further down on this PB page at http://www.dr-bob.org/babble/20050617/msgs/514305.html . But it’s like any other p-med, the correct dosage (if any) is the one that works for you personally. So you know the drill (much better that I do); trial-and-error experimentation while keeping a symptom tracking diary and then analyze the data collected.

I’m sure you’ve already reviewed the Prescribing Information document for Trileptal ( http://www.crazymeds.org/trileptalpi.pdf ). The Dosage and Administration section begins on page 33 for its use as an antiepileptic. Since the use of Trileptal for BP is off label, I’ve not seen any BP dosage recommendations from the manufacturer. But the AED dosage and administration guidelines do serve to define the safe dosage range. I wouldn’t take more than 2400 mg/day.

I’d say it’s safe to use the Trileptal dosage guidleines as if you were on a monotherapy treatment. I say this because the only other AED you have on board is Lamictal and there is very little drug-drug interaction between Trileptal and Lamictal (and vise versa). See the applicable drug-drug interaction information (e.g.; pg 42 and other related pages) in the Lamictal Prescribing Information document ( http://us.gsk.com/products/assets/us_lamictal.pdf ). However, I have no idea of the interactions of Trileptal and the other meds that you take.

> Lamictal 150mg
> Parnate 80mg
> nortriptyline 100mg
> Abilify 10mg
> Trileptal 600mg

Wow, you’ve got some big guns onboard.

> I am so damned impatient!

That’s understandable. You’ve been battling a long long time, so who wouldn’t be eager if even a glimmer of hope appears.

-- Ron


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poster:Ron Hill thread:511101
URL: http://www.dr-bob.org/babble/20050617/msgs/514502.html