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Re: SSRI's- question » Sarah T.

Posted by sedona on June 16, 2005, at 12:37:20

In reply to Re: SSRI's- question » sedona, posted by Sarah T. on June 16, 2005, at 0:46:46

Well, right now I am only taking 30mg of the Cymbalta because I didn't really notice a difference between 30mg and 60mg. I have always thought the Cymbalta made me a little tired. I take Adderall XR 30mg twice a day. I used to take 30mg once a day, but it seemed to have lost some of its effects and that is why I now take it twice a day. I haven't had a any problems with it, even at the higher dose. I was hoping it would help me lose some of the weight I have gained from antidepressants, but it hasn't.


> Hi Sedona. Thanks for your reply. May I ask how much Cymbalta you are on and how much Adderall? Does the Cymbalta seem to potentiate the effects of the Adderall and vice versa? What I mean is, I know Cymbalta is partly a norepinephrine (NE) reuptake inhibitor, and Adderall affects NE, too, a bit more than Dexedrine does, so I wondered about problems like palpitations, tremors, things like that.
>
> I think it's possible that the SSRI portion of Cymbalta might make it necessary to raise the Adderall dose. Although I don't have enough experience with Cymbalta, I do know that whenever I tried to combine an SSRI with a stimulant, the addition of the SSRI made it necessary to increase the stimulant dosage. In fact, the SSRI seemed to negate many of the benefits of the stimulants for me; however, I have met people who've successfully combined those two, without having to continually raise the stimulant dose.


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