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Re: Wellbutrin and anorexia in best friend

Posted by tygereyes on May 11, 2005, at 20:34:50

In reply to Re: Wellbutrin and anorexia in best friend » mworkman, posted by Chairman_MAO on May 11, 2005, at 20:26:31

> I seriously doubt this "increase in activity" is what is responsible for the seizure. What you are referring to I think is an "endorphin rush" following purging, which is why naltrexone seems to help bulimics. I don't know why they just don't give buprenorphine to "normalize" the endorphin system, though, as naltrexone can cause despair, dysphoria, etc. Oh, wait, I _DO_ know why, it's just absurdly sadistic reasoning ...

I thought that Naltrexone was often prescribed as an adjunct to antidepressant pharmacotherapy? What is the mechanism by which it would BOTH cause despair/dysphoria AND boost antidepressant response? I'm curious!


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URL: http://www.dr-bob.org/babble/20050510/msgs/496637.html