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Re: Topamax, GABA, and anxiety?

Posted by Cairo on May 4, 2005, at 19:01:17

In reply to Does dopamine cancel GABA anxiolysis?, posted by cache-monkey on May 3, 2005, at 16:06:19

Since one of the mechanisms of Topamax is augmenting the activity of gamma-aminobutyrate at some of the subtypes of the GABA-A receptor, why would it cause anxiety? I've titrated up to 100mg and gotten progressively more anxious. Today I cried off and on for no reason. Started after I took my morning dose. I get all sorts of paradoxical reactions to meds. Neurontin was ok, but gained weight and was too foggy. Am taking it for pain.

Cairo


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poster:Cairo thread:493198
URL: http://www.dr-bob.org/babble/20050504/msgs/493828.html