Posted by chemist on May 2, 2005, at 3:43:24
In reply to Re: why do antipsychotics have anti-depressant eff, posted by mogger on May 1, 2005, at 23:30:52
> chemist,
> one more question and then I promise I will shut up. As you say that higher doses it stops dopamine transmission. Do you think that 300mg of Seroquel would do that or is it a low to mid enough dose to have some benefit (i.e. not stopping dopamine transmission) as opposed to not. Many thanks for your advise,
> moggerhello there, chemist here...no bother, i apologize for not responding sooner...stopping transmission is a bit strong: putting the breaks on over-production and reuptake of DA by one or more specific receptors in a certain part of the brain to ease psychoses is perhaps more accurate...your question is likely best answered by experiment, as the dose you suggest might be (to *you*) more activating while to another it might still be sedating. i imagine that 25 to 50 mg per day is not going to ease psychotic breaks, nor would one ingest 1200 mg simply for a night's rest - the breakpoint from sedation may be absent or in, i suspect, the region you mention...sorry i can not be of more help, and do consider (with your doctor) a trial in the range you specify....all the best, chemist
poster:chemist
thread:491782
URL: http://www.dr-bob.org/babble/20050428/msgs/492566.html