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Re: benzos and libido » Paul Smith

Posted by ed_uk on April 11, 2005, at 9:58:59

In reply to benzos and libido, posted by Paul Smith on April 10, 2005, at 13:48:26

Hi,

>Which is the worst in your opinions, particuarly male libido?

I get the impression that clonazepam causes more sexual side effects than other benzos.

In the short term, diazepam does reduce my libido. I have never taken it long-term. I don't have enough personal experience with any other benzos to say what effect they would have on my libido, pdocs here much prefer diazepam to other benzos! My last pdoc never prescribed any other benzos!


Anxiety. 1994-95;1(5):233-6.

Clonazepam-related sexual dysfunction in male veterans with PTSD.

Fossey MD, Hamner MB.

Ralph H. Johnson Veterans Administration Medical Center, Charleston, SC 29401, USA.

Medication-induced sexual dysfunction can significantly interfere with patients' quality of life and lead to poor compliance. This retrospective study examined the records of 100 male veterans with post-traumatic stress disorder (PTSD) selected in alphabetical order from an active treatment file of 230 patients. Forty-two patients had received clonazepam (mean maximum dose: 3.4 +/- 1.6 mg/day) at some point during their treatment. Of these, 18 (42.9%) complained of significant sexual dysfunction (primarily erectile dysfunction). Eighty-four patients received diazepam (mean maximum dose: 52.1 +/- 29.7 mg/day), nine received alprazolam (mean maximum dose: 5.2 +/- 2.8 mg/day) and eight received lorazepam (mean maximum dose: 3.8 +/- 2.4 mg/day). None of these patients complained of sexual dysfunction during treatment with these three other benzodiazepines. Our findings suggest that benzodiazepines, particularly clonazepam in the current study, can be a cause of sexual dysfunction in many male patients. Prospective studies comparing the overall clinical utility of various benzodiazepines are indicated in this and other clinic populations.


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