Posted by ed_uk on March 19, 2005, at 18:20:17
In reply to Re: Hey Ed... » ed_uk, posted by Larry Hoover on March 19, 2005, at 17:21:59
Hi Lar!
>Since you have access to some superb databases....
I'm not at University for the next three weeks, I don't have access from home :-(
>But even if I think I get the dose of meds right (little or no pyschoactive effect), I have a hell of a time getting to sleep, and staying there.
I've certainly heard of opioids causing insomnia. Morphine is sometimes claimed to be more sedating than oxycodone, perhaps you could use it as an alternative to oxy in the evening and at night. Oral morphine is less potent than oral oxycodone, the conversion factor is about 1.5 (variable: 1-2). Opioids do sometimes induce vivid dreams, tolerance to this effects doesn't generally seem to occur.
Quite a few CNS reactions have apparantly been reported with ketorolac, including anorexia nervosa! Indomethacin is another NSAID which is known for its CNS side effects.
Just out of interest, have you ever tried flurbiprofen? I once read that it was a more effective analgesic than other NSAIDs, I don't know why this would be though- perhaps it was a load of rubbish!
>I've used temazepam and trimipramine for an extended period of time.
Do they still work as well as they used to? Have you tried zopiclone? It's claimed to be associated with less tolerance than temazepam.
Best regards,
Ed.
poster:ed_uk
thread:470781
URL: http://www.dr-bob.org/babble/20050317/msgs/472939.html