Posted by Ritch on March 13, 2005, at 12:44:13
In reply to Re: PameKlonoLithiLoft=Can't Think/Remember » Ritch, posted by smith562 on March 12, 2005, at 18:06:05
> > I would consider changing the WB > nortriptyline (Pamelor). A few years back I was on WB + Effexor (for AD's-with Depakote and clonazepam). I called it "Depaklonoeffexobutrin" and overall it was pretty potent combo for bipolar depression. However, I was still having really bad residual anxiety at times from the WB. I added 10mg of nortriptyline here and there during that time and got VERY good relief from the anxiety. I've also tried nort+Zoloft (which also worked pretty good), and nort+Celexa (not as good, blah). If you go the nortiptyline route, just take 10mg for a couple of weeks (the Zoloft will increase its blood level somewhat) and see what happens. It helped my ADD sx rather well. The anticholinergic effects.. really bad dry mouth.. is what made me not like it.. but on the plus side.. NO orthostatic hypotension.
>
> I am fairly certain adding pamelor would help. I was on imipramine/lithium/klonopin for a year with good results. I really hate to sound like a whiner .... I usually don't complain about side effects .... I have been on "dirty drugs" for years and very few side effects will stop me from taking a med if relieve my deading depression/anxiety. The thing I am scaried of with pamelor is the cognitive problems ... my work requires an intact cognition .... peoples lives depend upon it. Lithium and klonopin already cause some mild cognitive problems ... but add in a tricyclic and even simple mathmatics can be difficult.
>
> You know of anything without the cognitive problems of pamelor?
>
> Thanks
>
> Smith
I've tried imipramine, desipramine, doxepin, amitriptyline, and nortriptyline of the TCAs, and desipramine and nortriptyline were the least *fuzzy* of the TCA's. In fact, after a couple of weeks of taking them, things got sharper. If you haven't tried Pamelor, you might find it quite different than imipramine. That said, have you tried Stratterra or Reboxetine? I'm trying to think an NE reuptake inhibitor that doesn't have antihistamine effects. Another possibility is switching the Zoloft to Prozac. Prozac was the only SSRI that seemed to improve my focus.
poster:Ritch
thread:469590
URL: http://www.dr-bob.org/babble/20050312/msgs/470444.html