Posted by MoparFan91 on March 10, 2005, at 0:19:26
In reply to Re: Lamictal: Split doses, or all at once?????????, posted by qbsbrown on March 9, 2005, at 21:28:31
I'm on 200mg of Lamictal right now, and I originally took it all in the morning. Despite the long 33 hour half-life, when it was taken once a day, I wasn't getting optimal relief, and my mood would seem to drop close to the next dose. When I got up to 200mg in the morning, I felt a little more tired. Now, I've split the dose to 100mg 2xday, and it seems to be working in a more consistent way and providing better coverage for depression around the clock. So far, I have no side effects from Lamictal.
I think I metabolize meds a bit faster than average because I seem to need to take meds more times a day than the average person. I had the same with Lexapro (which has a long half-life). Once a day dosing all in the morning (even at the max dose) didn't provide coverage for depression relief for the whole day, and I would start swinging downward when nighttime came. I would have been better off with twice a day dosing for Lexapro.
poster:MoparFan91
thread:468748
URL: http://www.dr-bob.org/babble/20050308/msgs/469079.html