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Re: Eliminating Parnate poop-out? » EERRIICC

Posted by Optimist on February 8, 2005, at 10:51:06

In reply to Re: Eliminating Parnate poop-out?, posted by EERRIICC on February 7, 2005, at 15:35:22

> Found one at the CAMH (Center for Addiction and Mental Health), but it was a real hassle getting in there. Hope Parnate works out for you. How Parnate, or any antidepressant, works is really not known, so I figure I'll give the five day on and then one or two days off theory a try, just to see what happens. This is assuming I go back on Parnate (I'm on Mirapex 1.5mg t.i.d. right now)
>
> Eric

I'm pretty weary of you accepting my advice of a 5 on, 2 off schedule for your Parnate. Final decisions on your meds should defer to your pdoc and not some guy you met on an internet chat board if you know what I mean. :)

I'm not completely sold the reason for Parnate "poopout" is due to downregulating dopamine autoreceptors or some other dopamine mechanism. There could be many other variables behind your illeged "poopout" from; psychosocial factors, to depletion of dependent precursors/enzymes, a hidden bipolar diagnosis, etc... that's for your pdoc to decide. I am all for researching and arming one self with as much knowledge as possible, but it can be dangerous managing one's medication regimand. You need that objective view from a trained professional.

I think the best options to explore first would be to:
1. Make sure your micronutrient levels are up to snuff. i.e a high potentcy vitamin B-complex, inositol, phenylalanine/tyrosine, tryptophan/5-HTP, a good multivitamin/mineral. You would have to be careful with introducing the amino acids with MAOIs. More research on that would be needed.
2. Addition of low dose lithium, 0.4-0.8 mmol/L

And besides I'm not a doctor, I just play one on the internet. :)

Brian


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