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Re: ask SLS about nortriptyline » SLS

Posted by Maxime on February 3, 2005, at 21:19:48

In reply to Re: ask SLS about nortriptyline » Maxime, posted by SLS on February 3, 2005, at 3:18:03

I think I will try adding the nortriptyline. Lamictal makes me VERY depressed. Abilify isn't available in Canada, although I have wanted to try it. My trileptal is working very well though as a stabiliser. I'm bipolar type 2, are you? All I know is that I have to get off the Nardil and back to Parnate. I am going to lose my job if I stay on it. TOday I had to leave work because I was throwing up all morning from it. I also passed out again.

Maxime


> Hi Maxime.
>
> I saw my name tossed around, so I figured I'd chime in. I think it makes sense to try augmenting with either lithium or Lamictal first before moving on to more exotic treatments. I am currently taking:
>
> Parnate 60mg
> nortriptyline 100mg
> Lamictal 300mg
> Abilify 10mg
>
> I have once been on a comination of Parnate + desipramine + d-amphetamine + T4. Things like this are done, albeit infrequently. I would avoid imipramine and clomipramine, as they are a bit too serotonergic to be mixing with MAOIs. My personal experience with Nardil + imipramine was that I experienced serotonin syndrome. Choosing desipramine or nortripyline is probably best.
>
> The other thing, of course, is to try taking the Parnate way up to 120mg or higher. It can act like a different drugs at these dosages. Some study that I read 10 years ago suggested that high dose Parnate downregulated 5-HT2 serotonin receptors, something not seen at lower dosages. It was an animal study. (Sacraficing and decapitating humans was still frowned upon in those days).
>
>
> - Scott

 

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