Posted by SLS on February 3, 2005, at 7:20:21
In reply to Re: luvox working, posted by celticmom on February 3, 2005, at 6:55:10
Hi.
> I'm happy the Luvox is working for you. I can only say that Luvox is the only drug so far that has completely resolved my son's obsessive behavior.
It's wonderful when a drug delivers on its promise. Luvox was approved by the FDA specifically for OCD, not as an antidepressant. I am happy for you and your son.
> He's only on a very small dose - 25 mg - because he is SSRI sensitive and when we increased it too much, he became manic.How old is your son? Has he ever been manic while not taking medication? It is not impossible to have both bipolar disorder and OCD at the same time. In children, it is the mania that tends to develop first, and not the depression. I don't want for you to add another diagnosis to your son, but because this comorbidity does occur, it would be a good idea to watch for it. Like OCD, bipolar disorder is a result of brain dysfunction. With bipolar disorder, the longer it is left untreated, the greater is its biochemical grip on the brain, and the more difficult it is to treat. This phenomenon is known as the "kindling" of the brain.
I just wanted to express my concern. If I were in your position, I know I would not want to have my child take any more medication than is absolutely necessary. Knowledge is power.
- Scott
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J Affect Disord. 2002 Feb;68(1):1-23. Related Articles, Links
The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issues.Freeman MP, Freeman SA, McElroy SL.
"A growing number of epidemiological studies have found that bipolar disorder significantly co-occurs with anxiety disorders at rates that are higher than those in the general population. Clinical studies have also demonstrated high comorbidity between bipolar disorder and panic disorder, OCD, social phobia, and post-traumatic stress disorder."
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Vertex. 2003;14 Suppl Spec:5-6. Related Articles, Links
[The course of bipolar illness][Article in Spanish]
Lagomarsino A.
"Although Kraepelin submitted that manic depressive disease is a good-prognosis illness, further data showed that it follows an aggravating course as new episodes emerge. The Kindling model, introduced by epileptologist Goddard and adapted by Robert Post to bipolar disorder, is a possible explanation of the neurobiologic mechanism that underlies the worsening course of the illness. The presentation highlights relations between Kindling, mechanisms governing apoptosis, and the need of continuous treatment for an adequate control of the disease."
poster:SLS
thread:452307
URL: http://www.dr-bob.org/babble/20050202/msgs/452314.html