Posted by FaithT on January 26, 2005, at 0:19:58
In reply to Re: Long Term Effexor XR Usage...Scott~, posted by FaithT on January 25, 2005, at 23:40:58
*These studies can all be found on Pub-Med*Venlafaxine ER in adult outpatients with
generalized social anxiety disorder ~October 2004. In this placebo-controlled, multicenter, randomized, double-blind trial, 272 individuals with generalized social anxiety disorder received either a flexible dose of venlafaxine ER (75 to 225 mg/d) or placebo for 12 weeks. The study found that, "Venlafaxine ER was statistically significantly more effective than placebo as demonstrated by the Liebowitz Social Anxiety Scale total scores at weeks 4 to 12...Adverse events were similar to those reported in studies of venlafaxine ER in depression and generalized anxiety disorder. Venlafaxine ER was safe, well tolerated, and efficacious in the short-term treatment of generalized social anxiety disorder."
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Efficacy of Venlafaxine ER in patients with social anxiety disorder: a comparison with paroxetine:August 2004. In this double-blind, placebo-controlled, parallel-group study, 434 adults with generalized social anxiety disorder (SAD) were randomized to receive capsules of venlafaxine ER 75 mg to 225 mg/day, paroxetine 20 mg to 50 mg/day, or placebo for 12 weeks. The study concluded that, "Treatment with venlafaxine ER was associated with significantly greater improvement than treatment with placebo for all efficacy variables. No significant differences in efficacy variables were observed between the venlafaxine ER and paroxetine groups. The week 12 response rates were 69%, 66% and 36% for the venlafaxine ER, paroxetine and placebo groups, respectively. Both active treatments were generally well tolerated and were associated with a similar incidence of adverse events. This study shows that venlafaxine ER is an effective, safe and well-tolerated drug treatment for SAD."
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Venlafaxine compared with SSRI’s ~May 2002. This analysis of 32 randomized trials found that Effexor was significantly more effective than SSRI antidepressants, but not tricyclic antidepressants.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~Remission rates during treatment with venlafaxine or SSRI’s
July 2001. This analysis of 8 randomized, double-blind studies, concludes that venlafaxine resulted in better outcomes than treatment with selective serotonin reuptake inhibitors (SSRIs). 45% of the patients taking venlafaxine experienced remission from depression, compared with 35% of those taking SSRI’s and 25% on placebos.
poster:FaithT
thread:446637
URL: http://www.dr-bob.org/babble/20050124/msgs/447863.html