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Re: GABA receptors external to brain?

Posted by sabre on January 23, 2005, at 20:05:48

In reply to Re: GABA receptors external to brain? » sabre, posted by Larry Hoover on January 23, 2005, at 9:06:33

Thankyou Larry

I am looking at GABA-A receptors in relation to my social anxiety and my sister's epilepsy.

I suspect that these might be implicated because my sister has poorly controlled grand mal epilepsy which I read (in one article) is due to the GABA-A not binding with its receptors. They seemed to think partial seizures were due to insufficient GABA-A. I also have a sister who I suspect shows OCD tendencies....a neat freak.
My parents and other siblings are all shy. I don't know how much it bothers them. I hide my social anxiety so they may do so too.

I also found references to GABA in the retina.
Another sister has developed a rare retinal problem aggravated by stress. Sorry I don't know the name of it.

Serotonin receptors are found in the gut so I wondered if the same occured for GABA. The supplement GABA may have an effect on these receptors. Those using GABA think the blood-brain barrier prevents its uptake. Perhaps if you are deficient in GABA this route might become important?? I would like to know if anyone has had success with GABA supplements.

I am about to try Picamilon. If it is successful can you see any problems trying it for epilepsy, e.g. if you establish a regular dosage of Picamilon and then reduce it, could it lower your seizure threshold?

Thanks Larry. I was hoping you would shed some light on this!

sabre


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URL: http://www.dr-bob.org/babble/20050119/msgs/446478.html