Posted by jujube on January 21, 2005, at 14:23:15
In reply to TCAs/tetracyclics contraindicated w/ thyroid med?, posted by KaraS on January 21, 2005, at 0:27:11
Hi Kara,
It is my understanding that effects of TCAs and sympathomimetics may be increased when taken concurrrently with thyroid medications. I only came across one specific citing in reference documents I have on TCA interactions, and it was to Liothyronine (T3, Cytomel) and said the following: "Can enhance the effects of TCA. Abnormal heart rhythms can result. TCA blood levels may increase.".
Sorry I couldn't be more helpful.
Take care.
Tamara
> I'm supposed to start on maprotiline soon but I'm a little concerned about reading that it's contraindicated with thyroid medication, since I take thyroid hormone for hypothryoidism. Unfortunately the drug monograph and other information I've been able to find out are very vague on this issue. They mention thyroid medication as being contraindicated but they don't specify if they mean medication to treat hypothyroidism and/or hyperthyroidism.
>
> In Dr. David Burns' "The Feeling Good Handbook" he states: "use TCA with caution in patients with thyroid disease, or those taking thyroid medication; may trigger abnormal heart rhythms."
>
> My initial reaction was to assume that this was about hyperthyroidism but now I'm not so sure.
>
> I'm only supposed to start on a low dosage of the maprotiline. I think that the last time I took it I was already on thryoid hormone but I'm not positive. Maprotiline helps me sleep and it works well in preventing panic disorder. The TCAs/tetracyclics have always worked so well for me on anxiety. I'd hate to have to give up this remedy.
>
> Kara
>
poster:jujube
thread:445050
URL: http://www.dr-bob.org/babble/20050119/msgs/445269.html