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Re: memantine

Posted by SLS on January 14, 2005, at 8:07:31

In reply to Re: memantine JackD, posted by lars1 on January 14, 2005, at 6:45:36

> > Hmm, haven't been able to find anything yet, here's some stuff I did stumble upon though that I thought were interesting while I looked though:
> >
> > http://www.ntii.com/products/index.shtml
> > http://www.fda.gov/ohrms/dockets/ac/03/briefing/3979B1_01_ForestLabs-Memantine.pdf
>
> Thanks for the links. I hadn't seen those. The PDF is the most comprehensive report on memantine that I've found. I suppose it should be taken with bit of skepticism since it looks like it's basically an advocacy document attempting to persuade the FDA to approve a new drug.
>
> > I could've sworn I read about it being used at 40mg for Depression on-line (the links I provided only show it being used at 40 for Neuropathic pain). My doctor did call Forest Labs however during a session with me and was told by a drug rep that a 40mg depression trial was underway, so unless he was confused there must be some validity to this claim. I'll keep trying to see if I can dig anything else up. Thanks for that other link too.
>
> Did Forest Labs have anything else useful to say over the phone that you could share? It sounds like they confirmed that they thought it was a legitimate (though unproven) thing to try for depression?

Memantine definitely had a passing antidepressant effect for me at 20mg. It lasted for about a week. In Germany, I believe it has been used for Parkinsons and depression along with Alzheimers. The feeling of drunkeness that I experienced after a few days at 40mg scared me, though. If people begin to report similar reactions that disappear with time, I might try it again.


- Scott

 

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poster:SLS thread:439981
URL: http://www.dr-bob.org/babble/20050113/msgs/442052.html