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Re: The radio inside my head » D minor

Posted by Ritch on January 10, 2005, at 13:38:41

In reply to Re: The radio inside my head, posted by D minor on January 10, 2005, at 10:42:31

> > > Thanks for your reply dm,
> > >
> > > My Diagnosis is Major Depression with psychotic features. I take 15 mg of the Zyprexa and 60 mg of Cymbalta. The funny thing while my depression, voices and other hallucenations are helped by meds, this radio issue is not. I wonder if my issue could be a problem with racing thoughts as well, rather than a hallucenation.
> >
> > Serotonergic AD's (while helping with depression and anxiety) tend to cause a repetitive music thing in my head that's not an OCD thing or even necessarily unpleasant and not a hallucination either, but I think it has something to do with a temporal lobe activation from the AD. Stuff that I've found that dampens that particular set of symptoms down really well are anticonvlsants, esp. depakote, trileptal, or neurontin.
>
> I was going to say something similar. Depakote put a stop to the hypomanic (racing thoughts) radio head. Also, while I was on Topamax I never had a problem with it. I was on Topamax when my dx was MD with psychotic features (it has since changed to Bipolar w/psychotic features). I guess it can augment ADs effect or something along that line. Forgot to mention that I'm also taking Abilify, which I have found to be the absoulute best AP (only I find the side effects hard to handle).
>
> Best wishes,
> dm
>

Don't want to go off on too much of a tangent here... but when I was reading the monograph for Abilify it notes that it has a moderate affinity for the serotonin transporter. Also, given the exceptionally long half-life of 75 hrs or so, that stuff should have a whopping accumulation effect. I just wonder if some of the akathisia that is often reported from taking Abilify has perhaps more to do with that mechanism rather than the D2, D3, etc. receptor effects? Just thinking out loud a little...


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URL: http://www.dr-bob.org/babble/20050108/msgs/440163.html