Posted by ed_uk on December 31, 2004, at 17:04:27
In reply to Re: TCAs-desipramine, posted by banga on December 31, 2004, at 16:24:18
> I have not tried desipramine. If it causes less weight gain, wow it could be a great option.
Hi Banga!!
Weight gain isn't often reported with desipramine but I'm sure that it's possible! Some people have even reported weight loss. As far as I know, desipramine is a weaker antihistamine than nortriptyline and also a weaker 5-HT2 antagonist- this suggests that it would be less likely to cause weight gain.
> But in terms of 5HT2a blocking...doesn't that help with anxiety in some cases?
Yes, I think that it probably does in some cases. Noradrenergic drugs such as nortriptyline, lofepramine and desipramine do at times cause anxiety as a side effect. On the other hand, NRIs can be useful in treating panic disorder. Personally, I haven't noticed any change in my anxiety since I've been taking lofepramine.
> But thanks for the desipramine hint. Now I have to think how I will pose this to my pdoc after just convincing her that nortryp is the next logical choice.
Well, it is usually necessary to try several different drugs to see which you prefer..... if only our responses to drugs were more predictable.
Regards,
Ed.PS. Happy New Year!
poster:ed_uk
thread:434951
URL: http://www.dr-bob.org/babble/20041228/msgs/436103.html