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Re: MAOi's vs Wellbutrin + SSRI » gardenergirl

Posted by Optimist on November 30, 2004, at 23:19:19

In reply to Re: MAOi's vs Wellbutrin + SSRI » Optimist, posted by gardenergirl on November 30, 2004, at 22:31:57

> Hi Optimist, I like your posting name.
>
> I was on Celexa and Wellbutrin before I was diagnosed with atypical depression. Once I got that diagnosis and after some time doing research and soul searching, I got off the SSRI/Wellbutrin and started Nardil at the recommendation of my T. It has been a godsend for me. There was an immediate change in how I felt. The results were much better than any SSRI or combo I've tried. Now admittedly I didn't try them all because MAOI's were "the gold standard" for atypical depression, and I figured why not try what's supposed to work best?
>
> But there is no comparison for me in the differences between the two. I'm not sure I can even quantify the effect from SSRI's now that I know what normal really feels like again.
>
> Good luck whatever you decide.
>
> gg
>
>


Thanks Gardenergirl for the input. I picked the name mainly because I was a huge motivational/self help/positive psychology junky. I seem to struggle with the optimism at times though as we all do from time to time. I guess that's the effect depression can have. It runs deep in my family, so I'm sure there is a biological contribution for sure in my case.

The MAOi's intrique me a lot in terms of their effectiveness. They seem to be a head above all the other AD's for most depression related illnesses. I'm more partial to Parnate as it seems to have a more activating profile as I need help in that department. I'm not sure if I have atypical depression or not. My depression is characterized as mostly lack of energy and motivation, mood reactivity, sensitivity to rejection, and some social anxiety. Those characteristics seem to imply atypical depression it seems but my pdoc doesn't necessarily think so. We're still ironing that out.

I thought I may have had some form of bipolar due to me being extremely moody, but I've never had an extended period of hypomania. I can never sleep much less than 8 hours a night, and with the AD combo I'm currently on my pdoc said I'd go hypomanic/manic most definitely. My pdoc said I was on "rocketfuel" do to all the activating meds I'm on. She seems quite surprised I don't have insomnia issues, but sleep has never been a problem with me. My grandmother was bipolar 1, and my sister may be as well. We're still trying to figure that one out.

I'm supposed to refill my Prozac tomorrow. I suppose I haven't given it a fair trial yet as I've only been on it for a month now. The Wellbutrin and Adderall for much longer. Since I know there is a 5 week washout period with the Prozac though, I'd like to discontinue that as soon as possible if I were to give the Parnate a shot.

The Parnate does seem to be up my alley though. I don't think my pdoc would have a problem prescribing it. She seems to be less conservative in that regard. I know she prescribes multiple drugs, benzo's, and stimulants so I don't think it should be a problem.

I had a 6 month run of Moclobemide last year, but it didn't seem to be having much effect. I was on twice the recommended max 1200mg per day, and it felt like I was on a placebo. No side effects, and no apparent antidepressant effects either.

Wish me luck!


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URL: http://www.dr-bob.org/babble/20041128/msgs/422619.html