Posted by Larry Hoover on November 30, 2004, at 11:15:43
In reply to Re: drug-induced illness, posted by JACJ on November 30, 2004, at 10:18:04
> Very Interesting research. Do you think one should get MRI, etc. after comming off the drugs? Part of me wants to find out what damage has been done, if any?
I don't know that anyone has even come up with an adequate model of what brain dysfunction is associated with dyskinesia. Even if the MRI showed something, what then?
Current theory is that there is an oxidative stress effect of neuroleptic medication, and that may lead to some sort of damage that produces dyskinesia. For that reason, trials of e.g. the antioxidant vitamin E have been done. The benefit is probably there, but it is mild. Interestingly, I see that these trials only used one form of vitamin E, alpha-tocopherol, whereas it is gamma-tocopherol that is thought to be most neuroprotective. For that reason, I suggest that a trial of "mixed tocopherols", or a vitamin E product that specifically lists gamma-tocopherol on the ingredients, might be in order.
Lar
poster:Larry Hoover
thread:422246
URL: http://www.dr-bob.org/babble/20041128/msgs/422344.html