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Re: dothiepin

Posted by ed_uk on November 25, 2004, at 7:48:29

In reply to Re: dothiepin » ed_uk, posted by KaraS on November 23, 2004, at 14:18:05

Hi Kara,

There doesn't seem to be any good reason why dothiepin is so popular. Its side effect profile resembles amitriptyline but it's a bit less anticholinergic. Its efficacy has been questioned though. You're not missing out on anything. Might as well just take a low dose of amitriptyline if you want to mimic the effect of dothiepin! It doesn't have any major advantages over other TCAs. Also, it increases the risk of developing coronary heart disease.


Regards,
Ed.


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