Posted by King Vultan on November 22, 2004, at 8:29:33
In reply to Parnate and Mirtazapine Combo, posted by james_glasgow on November 21, 2004, at 17:21:18
Theoretically, there is a risk from Remeron's alpha-2 adrenergic blockade releasing norepinephrine (and perhaps serotonin--don't have my reference with me today and can't remember exactly), but trazodone has the same blockade and is widely used for MAOI insomnia. I think it's probably okay, but I think it's a good idea to start out at a low level of a drug like this just in case there are adverse effects. Surmontil/trimipramine, which is a sedating tricyclic, might also be worth considering, and I believe this is perfectly safe to use with an MAOI because it has no obvious way of releasing any additional amines. Doxepin is a little riskier but is also probably still okay. It would have a greater tendency to induce weight gain than Surmontil; although, I believe the latter drug would also have some ability to do so.
Todd
poster:King Vultan
thread:418727
URL: http://www.dr-bob.org/babble/20041118/msgs/418893.html