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Re: resuming the thread » zeugma

Posted by KaraS on November 6, 2004, at 18:47:35

In reply to resuming the thread » KaraS, posted by zeugma on November 5, 2004, at 19:40:12

> I've always been underweight. Provigil, strangely, made me gain weight. I think it has to do with the orexins that are deficient in my brain. I tried to write an explanation at the post you guided me to.

Yes, I read that. I understand. I have had some prolonged periods in my life where I couldn't eat because of extreme anxiety. That's just as bad as having to worry about weight gain.

> > > >
> > > > > So you think that there's still movement disorder risk to using amisulpride at AD dosage level?
> > >
> > >
> > > Yes, there is a risk, which increases with duration and dosage.> >
> >

I have a friend who just started on low-dose Seroquel for anxiety (as an addition to Wellbutrin). I have not said much to him about the possible side effects but I have wanted to. I wanted to check out how valid my concerns are first. I am also afraid that my mother's doctor is going to prescribe Seroquel for her. I wish he would prescribe a small amount of doxepin or maprotiline instead. How much should I worry about the cardio effects on a woman in her mid-70s though?


> >
> > > > > > Something you might want to consider is Abilify. It is a partial agonist of D2 receptors. In theory, if your D2 receptors are overly sensitive, then Abilify will desensitize them, much like buspirone is thought to desensitize the 5HT-1A receptor. I have also read claims that Abilify is the only AP besides clozapine that does not carry the risk of tardive dyskinesia. I would say Seroquel would be the least likely of the others to induce TD.
> > > > >
> > > > > My pdoc recommened Abilfy to add on to something else for my potential "soft bipolar'" condiiton - if in fact i have that. If so, might be able to kill two birds with one stone.

Abilify is a consideration for the future. It's not my first choice now though. I'm leaning towards starting on Parnate. I've been depressed and dysfunctional for far too long now. It's time to go for the gusto I think.


> > > > >
> > > That's a commendable aim. I thought I was killing two birds with one with the nortriptyline/methylphenidate combination. As my pdoc said, though, I seem to have killed one bird- the narcolepsy, not the ADD.

I thought it was the other way around.

>> Ritalin does not really work for my ADD, and it creates anger and impulsivity during the crash- which is pretty serious considering I often work while the crash happens. I'm doing the 30:30 mg dosing now, in an attempt to forestall this. I took only the 30 mg dose in the am today, and even without anyone to direct the anger against, the crash is pretty bad- I lose the small amount of coordination I have, I fumble with my wallet and everything spills out, I get this 'trance'-like feeling that is not pleasant. Ritalin does not make this disappear. It makes the 'trance' a momentary event. That is the 'wakefulness' effect. It is not a feeling of increased energy at all. It is feeling in a trance less often. It's so odd.

I can only imagine since I haven't experienced anything like it. It doesn't sound like you are able to be upfront about any of this with the people you work with or for. That must make it all the more difficult.


> > > Abilify MIGHT not be an agent that causes TD. It is still a new med so it is still uncertain, but I recall reading an article that compared its structure to clozapine, an agent known not to cause TD.

Yes, it's always to soon to say for sure until a med has been around for a long time and tested out in the real world.

> Is tianeptine another of those French drugs that causes spontaneous orgasms? That sounds like a reason to to think well of it :)

I'm sure there are worse side effects but, actually, I would need that particular side effect now like I'd need a hole in my head.


> > > > Thanks, as always for the info. I assume it's still to early to ask you how the 50 Ritalin LA is going?
> > > > >
> > >
> > > It is a rough ride. I have noticed that the afternoons are generally bad on the Ritalin, which could mean that the 20 mg I take at noon does not ward off the crash. (I take 30 mg am, which does not make me irritable, just tired as usual but with slightly improved focus.) My job requires that I stay focused through the afternoon. It could be that I need to try 30 mg pm, or maybe ritalin is not the way to go. At any rate, the 30-20 mg dosing schedule is not working out.
> >
> > I'm so sorry to hear that. I assume that you'll go up to 30 for your second dose. It doesn't sound like it will be any miracle result for you but it may allow you to function better until you figure out your next move.
> >
> > K
> >
>
> By the way, are you seriously thinking of Parnate now?

Yes, very seriously. I just left my doctor a message to that effect. It's one of the most powerful ADs there is and it might have the potential to reduce the density of the DA autoreceptors. All indicators seem to be pointing in that direction now. I'm terrified to try it though for many reasons - the biggest of which is that it seems like it's one of the strongest, most comprehensive ADs. If this doesn't work, what hope would I have left?

What did you and your doctor decide your next move should be?

Kara


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poster:KaraS thread:406397
URL: http://www.dr-bob.org/babble/20041103/msgs/412685.html