Posted by SLS on October 29, 2004, at 23:23:55
In reply to Prolactin levels increase cause weight gain? HELP, posted by iris2 on October 29, 2004, at 18:51:06
> It is my understanding that increased prolactin does cause weight gain.
Yes it does. I know one woman who gained weight primariliy in her tummy from taking Risperdal, an AP known to increase prolactin. Amisulpride will certainly do this, but I'm not sure at what dosages. Sulpiride, a related drug, is notorious for increasing prolactin.
> Will taking bromocriptine with it which should decrease the increased prolactin help with the ever increasing weight?
Bromocriptine will certainly reduce prolactin secretion, but it is no longer considered a first choice because of its side effects. I believe cabergoline (Dostinex) has supplanted bromocriptine for hyperprolactinemia.
Amantadine might be a better choice. Not only will it reduce prolactin, but it has the ability to reduce weight-gain due to AP induced changes in glucose / lipid dynamics. It has been used with success when used with Zyprexa.
One indicator of increased prolactin is a disturbance in the menstrual cycle.
Your focus on body weight is not silly. It is part of the package in your case.
Good luck.
- Scott
poster:SLS
thread:408878
URL: http://www.dr-bob.org/babble/20041029/msgs/408955.html