Posted by Racer on October 24, 2004, at 13:10:39
In reply to Re: cymbalta, posted by ravenstorm on October 23, 2004, at 23:21:03
I can't totally agree with you about the correlation between start up and withdrawal, because I didn't have any significant adjustment problems with Effexor, but I sure as [warm place] did have withdrawal problems. Missing a single dose put me out of commission for about three days, and it took about eight months all told to taper down from 225 mg -- which was still, shall we say, uncomfortable.
Cymbalta hasn't been in clinical use long enough yet to know what the overall withdrawal picture will be, but there were fairly long term studies done on it premarketing. I haven't seen anything about withdrawal effects in anything I've read. I would expect to see something by now, though, if it were going to be as much of a problem as it is with Effexor. What's more, my doctor -- who does stay up to date on these things -- says that he's not expecting withdrawal problems with it. He does, by the way, state clearly and emphatically that withdrawal from Effexor is a very real problem, and says that the expected LACK of similar problems with Cymbalta is the biggest selling point for him.
That's just an opposing viewpoint. (And I don't remember any withdrawal problems from Paxil, by the way, despite a fairly high dose for several years. All I remember is *finally* feeling awake again!)
poster:Racer
thread:406326
URL: http://www.dr-bob.org/babble/20041024/msgs/406647.html