Posted by Michael Bell on October 23, 2004, at 14:15:13
In reply to Re: THEY'RE HERE!!, posted by jboud24 on October 20, 2004, at 0:55:38
Well, it's only been about a week since I started taking Buprenorphine and Proglumide for social phobia, so bear in mind this update is by no means conclusive.
Here's what I've found:
BUPRENORPHINE: I only took it for about 4 days, .4 mg/day under the tongue. The effects are similar to codeine, except there's also an antidepressive type of feel to it, and it doesn't cause as much spaciness as other opioids I've tried (codeine, percocet, etc.) It's similar to other opioids in that it definitely reduces has an affect on the effects of outside stressors. Things that used to be a big deal just don't seem like such a big deal when on buprenorphine. The reason I only took it for about 4 days is because it caused stomach cramps, diarreah and some insomnia. Also, I wanted to see what the effects of Proglumide are without the influence of Buprenorphine. So is it good for Social Phobia? More time is needed before I can give you a definitive answer.
PROGLUMIDE: I'm very excited about this drug so far. It's only been a few days that I've taken this after discontinuing Buprenorphine (for the time being), but already I can tell you of some effects. First, Proglumide completely wiped out the irritable bowel symptoms I've been experiening for about 2 years. Even when I was on 1mg/day of Klonopin, I would get very anxious right before a bowel movement (sorry if this is too much info). The proglumide has ended that completely. Also, it has an anxiolytic action on its own, in that I don't anticipate social defeat when on it. The Klonopin is great for wiping out the physical symptoms of anxiety, but I still would have that feeling that my social interactions wouldn't go well. The Proglumide has lessened the anticipation of social defeat, so in a way I believe it could truly be prosocial. However, I want to give it a few more weeks to make sure this is not a placebo effect, and I'll update the board in the future.
> How is the buprenorphine working out Michael. I'm interested in the effect of opiates and social anxiety. Please give me a heads up if you find it works well for depression and/or especially social anxiety. And if you could, or have the experience, compare its effects to hydrocodone or codeine.
> Thanks, and best of luck