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Re: major anxiety, don't know which med to blame » upsndowns

Posted by Ritch on October 20, 2004, at 11:35:23

In reply to major anxiety, don't know which med to blame, posted by upsndowns on October 19, 2004, at 18:53:40

> Over the past three or four months, my anxiety level has soared to the point where I am afraid, to the point of almost paranoia, of being in my own house alone, of the dark, of going anywhere unless I am forced out of the same house that I am afraid to be in.....and at the same time, I do not want to be out of the house almost to the point of agoraphobia. I have been diagnosed BPII with hypomanic states of irritability and hostility but have been in the more depressed part of my cycle lately. I take 5mg of Abilify, 36 mg Concerta, tranxene prn and ambien for sleep. Does anyone have experience like this as a side effect of any of these drugs? I have been on them for several months, almost a year with Abilify, and it has until lately been the best thing I have taken, bar none. Oh, yes, I also take a smidge....25mg...of nefazadone. Please, everyone, I am getting desperate about this situation, it is impacting my life in a very negative manner, as you can imagine. Thank you for any help and advice.

Abilify can cause akathisia (restlessness), the nefazodone metabolite can induce anxiety, and the concerta could aggravate the agoraphobic stuff. I've had a really bad experience with taking stimulants with antipsychotics in the past (inducing panic). Taking ritalin with Depakote worked out ok. The stim+antipsychotic might be depleting GABA.


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