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Re: permanent damages by antidepressants ?

Posted by linkadge on August 29, 2004, at 18:01:25

In reply to Re: permanent damages by antidepressants ?, posted by theo on August 29, 2004, at 17:18:59

The only thing that I can offer for consoladation is the following.

Certain people are genetically missing MAO-A genes. Which means that they are virtally devoid of MAO-A. They have elevated serotonin and norepinephrine. Do these people's brains naturally dammage themselves ???

I think that serotonin levels vary from person to person. If you take excessive doses of AD's for long periods of time I can see there being a problem, but I think that the correct dose is probably not harmful.

Anyother thing, If I recall correctly, is that the only studies that he sites, are the ones that used fluoxetine in doses of 50-100 times the maxiumum human dose.

Another thing, is that depression most of the time, is neurodegenerative by nature. The majority of the well planned studies show that
*untreated* depression leads to significant hippocampal atrophy, and that antidepressant treatment ameliorates that shrinkage. It could be quite possible, that you would be a lot *worse* if you didn't medicate.

My mother describes my great-grandmother who went through 4- clinical depressions in her lifetime, *pre antidepressants*. She said this: "she recovered from every depressionm but a little peice of her was not the same"

Linkadge


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URL: http://www.dr-bob.org/babble/20040825/msgs/383795.html