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Re: Gabitril to cope with Nardil insomnia » jlbl2l

Posted by chemist on August 21, 2004, at 10:07:27

In reply to Re: Gabitril to cope with Nardil insomnia, posted by jlbl2l on August 21, 2004, at 4:07:02

hi jason....i too am interested in this one, although it's not at the top of my list, simply from personal bias in that i didn't give it enough time and/or it just didn't work for me in the dose prescribed. all that said, i do have a few pubs, although somewhat dated (like my parnate ones), when it was being touted early-on for mood stabilising properties. the lit i have jibes with your assertion in re: GABA reuptake inhibitor. what i am curious about is what the action of the drug is in the absence of a good amount of GABA already in the synapse, as i am not aware if gabitril agonizes any of the GABA receptors and/or enhances chloride and/or calcium flux.....let us know if you have any word on this, and all the best, chemist

> chemist,
>
> i am also interested in gabatril. from the user experiences i have heard it is is very odd drug -sometimes it keeps people more awake and have increased anxiety, while some people sleepy and calm. its basically a gaba reuptake inhibitor. Nardil also possesses gaba reuptake properties with its metabolites, so its interesting that by using gabatril -> nardil. just some random thoughts...
>
> jlbl2l


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