Posted by caraher on August 5, 2004, at 13:01:04
In reply to Re: CYMBALTA - With Drug Approval, Lilly Sighs Relief, posted by bob on August 5, 2004, at 2:14:19
> I'm really not sure what this drug is bringing to the party that Effexor XR isn't already doing. Surely it will have astounding sexual side effects, delayed weight gain, withdrawl syndrome, urinary hesitancy, and so on, and so on. I guess you never know until you try, but my body can't take these "trials" very well anymore. Is there anything novel about this drug, other than the ratio of reuptake being more towards norepinephrine than Effexor?
I did some reading about trials completed to date and got the impression that sexual side effects weren't as bad. Nothing about withdrawal syndrome but my understanding is that it has a half-life of something like 14 hours, which my amateur grasp of such things suggests might make withdrawal a problem.
The trouble is that based on what we know about the systems it works on, kinetics, etc. I totally sympathize with saying it's not a whole lot different from Effexor. But you can also make exactly the same argument to the effect SSRIs are all basically the same, so why should there be more than one available? But it's pretty clear that not all SSRIs are created equal, which makes me inclined to think that there's plenty of room for another option like Cymbalta alongside Effexor.
poster:caraher
thread:374053
URL: http://www.dr-bob.org/babble/20040805/msgs/374378.html