Posted by caraher on August 4, 2004, at 17:42:59
In reply to Re: Cymbalta/Duloxetine--Something's Up...YES!, posted by Marilyn on August 4, 2004, at 17:32:46
> Actually Cymbalta (duloxetine) is just another SSRI anti-depressant that also acts on nor-epinephrine (nor-adrenalin). It is comparable to Effexor (venlafaxine). Thus this new "miracle drug" offers potentially just as many horrendous side-effects that people already experienced on the other SSRIs.... and these people are definitely not so happy!That's basically my understanding, that it's kinda like Effexor in terms of the neurotransmitters it acts on, but with different kinetics and possibly other differences I'm not competent to speak to, being neither a chemist nor a neurobiologist.
Certainly Cymbalta is solidly in the "marketing hype" phase of its use as an antidepressant. Certainly there are people who will react badly to it, just like pretty much every other drug. I think the truth for most patients, as always, will lie somewhere in between Lilly's claims and the tales of horror so readily cataloged on the web.
poster:caraher
thread:208072
URL: http://www.dr-bob.org/babble/20040730/msgs/374118.html