Posted by SLS on July 27, 2004, at 20:50:20
In reply to Amisulpride,Mirapex,Requip...?, posted by iris2 on July 27, 2004, at 20:04:49
Hi Iris2.
It will be interesting to see what suggestions some of the newer members in the community have to offer you.
What was your experience with Effexor the very first time you tried it?
I would be very interersted to know how you respond to milnacipran. If you decide to try it, please keep us informed of your progress with it.
One drug that is not often mentioned here is sibutramine (Meridia). I know one pdoc in Princeton who swears by it. Sibutramine was originally developed as an antidepressant, but ended up being approved as an anti-obesity agent. It inhibits the reuptake of both 5-HT and NE, and exhibits properties in rat brain in vivo suggesting DA reuptake inhibition and/or release as well, most likely the result of its metabolites. A drug company was recently developing one of the enantiomers, r-sibutramine, specifically as an antidepressant. Unfortunately, it ran out of money for the project.
I have sibutramine on my list of things to try. I probably would have tried it by now if my medical insurance were to have paid for it. Meanwhile, I am waiting for Cymbalta to be approved. I'm sure you are already aware that this dual action SNRI (serotonin-norepinephrine reuptake inhibitor) antidepressant is to be decided upon by the FDA for approval in late September.
Have you ever tried adding a mood stabilizer?
- Scott
poster:SLS
thread:371386
URL: http://www.dr-bob.org/babble/20040724/msgs/371395.html