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Re: Neurogenesis and Depression: still an open deb linkadge

Posted by SLS on July 23, 2004, at 9:48:03

In reply to Re: Neurogenesis and Depression: still an open deb, posted by linkadge on July 23, 2004, at 8:52:40

> Generally bipolars have significant decreases in grey matter both in the frontal cortex, and in the hippocampas. Lithium increases BDNF in the frontal cortex as well as in the hippocampas.
>
> Frontal cortex hypofunction is seen in quite a few mental disorders but especially in bipolar. This is why some bipolars can actually somewhat stabalize with stimulants, because they activate the frontal cortex.
>
> In any respect, repair of the frontal cortex's functioning can reinstitute control. Frontal activation shuts down hyperactive limbic activity, and perhaps leading to more stable moods.
>
> Linkadge


Thank you for such an excellent synopsis, Linkadge. Where did you get most of your information from? I could use a good review.

I can only pray that we can find something for me that works and that these areas of atrophy can be restored. I can't begin to imagine how much damage has been done at this point. I wish I could tolerate lithium. It makes me feel significantly worse.


- Scott

 

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