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Re: Maprotiline (Ludiomil) - Comments?

Posted by KaraS on July 19, 2004, at 16:26:11

In reply to Re: Maprotiline (Ludiomil) - Comments?, posted by King Vultan on July 19, 2004, at 7:32:19

> > Maprotiline (Ludiomil)
> >
> > This is one of the few drugs I haven't tried. I keep forgetting about it.
> >
> >
> > - Scott
>
> The receptor chart in "Psychotropic Drugs" shows it as a selective NE reuptake inhibitor similar to desipramine or nortriptyline but somewhat more sedating. Structurally, it is a secondary amine similar in that way to those two drugs--no doubt, this is where the NE selectivity comes from--but it is a non-tricyclic, having a weird bridged center ring. There is a superficial resemblance to a tricyclic, however.
>
> Todd


Actually I think I've seen it referred to as a tetracyclic.


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poster:KaraS thread:367535
URL: http://www.dr-bob.org/babble/20040719/msgs/367859.html