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Re: Anyone got psychotic from Mirapex (Pramipexole

Posted by rod on July 17, 2004, at 6:13:03

In reply to Re: Anyone got psychotic from Mirapex (Pramipexole)?, posted by SLS on July 16, 2004, at 16:44:07

> Hi Roland.
>
> > And the Likelyhood to develop psychosis due to Pramipexole is relatively high.
>
> How high is high? Although I am aware of this as a possible side effect, I have never heard the phrase "relatively high" used to characterize it. I don't think it is so high as to be scared of.
>
> **************************
>
> From www.rxlist.com
>
> "The events listed below occurred in less than 1% of the 1408 individuals exposed to MIRAPEX:
>
> Nervous system: agitation, CNS stimulation, hyperkinesia, psychosis, convulsions. "
>
> ******************
>

Hi Scott,

Ok, you are right about this. I didnt look up the numbers before I posted. But now I am a little confused about psychosis vs. Hallucinations. Arent hallucinations also regarded as psychotic reaction? I thought one can have psychosis without hallucinations, but no hallucinations without psychosis. By saying psychosis I also meant hallucionations.

from rxlist.com - Warnings Precautions
"..hallucinations were observed in 9% (35 of 388) of patients receiving MIRAPEX, compared with 2.6% (6 of 235) of patients receiving placebo.."

And by saying relatively high, I meant compared to standard antidepressant treatment, where hallucinations/psychosis seem to be rare (also average of 1/1000, varying from drug to drug). I mean, I dont see any warnings about hallucinations in the prescription information from ADs like in the one from Mirapex.
And my doctor seems to be a bit overcautious, because once a patient jumped out of the window on pramipexole, because the devil was after him... Although this happened in a study for pramipexole for deficit syndrome, some years ago, and not for depression. Maybe this was just bad luck... Since then, he does not have a good feeling prescribing pramipexole (and I am the first one since then).

Anyways, I am hoping everything goes well on pramipexole.

thanks for your opinion and time
Roland


>
> Of the few dozen people that I have seen use it on PB, I haven't seen anyone describe anything like psychosis.
>
>
> - Scott
>


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poster:rod thread:366876
URL: http://www.dr-bob.org/babble/20040714/msgs/367075.html