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Re: Going through Effexor Withdrawl now Larry Hoover

Posted by SLS on July 14, 2004, at 7:06:34

In reply to Re: Going through Effexor Withdrawl now SLS, posted by Larry Hoover on July 13, 2004, at 20:29:11

Hi Larry.

> Hey Scott. How ya doin', buddy?

Crappy. :-) Thanks for asking. I think I'll stop by the Alternative board more often to pay visits.

> Anybody who can work "teleologically" into a sentence, with skill, has my support.

I've been keeping that one in my back pocket for a special occasion.

> I've been studying the literature, and plan to write a review article on the subject of antidepressants and suicide.

I look forward to reading it (as much as my depression will allow). Where will you be submitting it?

> Overall, suicide rates are declining, while SSRI prescription rates are increasing. There are two distinct effects, but the summary statistic is that suicides are reduced by SSRIs, notwithstanding temporary increases in susceptibility.

I know. Even if antidepressants do exacerbate depression in vulnerable individuals, the net effect of their use in the general population is, thankfully, a reduction in the rate of suicide. However, beyond the bottom line of the *interpretation* of statistics is the fact that these drugs do lead to the commission of suicide in certain individuals who would not have done so were they not to have been treated with a provocative medication. Everyone *must* recognize the fact that there exists such a thing as IATROGENIC SUICIDE. Hopefully, this can be accomplished without using any one drug unjustifiably as a scapegoat.

This would be an interesting use of statistics: Treat 500 people with Prozac and 500 people with placebo. In the active treatment arm, take the number n of non-responders as a group and determine the rate of treatment-emergent suicidal-ideation. Now, take the same number n of randomly chosen non-responders to placebo and compare the rates.

I am very glad to see that you have chosen to come back. I only wish that I could read the volume of the posts you write.


- Scott

 

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