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Re: Sorry - Above post meant for » Frisky_Cat

Posted by SLS on July 11, 2004, at 7:39:29

In reply to Re: Going through Effexor Withdrawl now, posted by Frisky_Cat on July 11, 2004, at 5:28:39

> I have to protest the comments below. There is no hard evidence that antidepressants increase depression.

Yes there is. There is enough to be actionable.

These are powerful drugs eliciting unpredictable effects on a brain that we have very little understanding of. Many drugs produce depression as a frequent side effect. Drug manufacturers are required to include this fact in the packaging of their products. It makes for a long list of very diverse drugs. Antidepressants are not teleologically exempt from producing undesirable mood alterations because they have some sort of biological "safety" that permits only antidepressant effects and precludes depressogenic effects. For any given individual, there may be certain antidepressants (or any other type of drug) that will exacerbate the clinical depression and induce suicidal states. Prozac has, and will continue to cause suicides as long as prescribing physicians continue to think like you do.

> The most logical explanation for the fact that sometimes people who take antidepressants commit suicide is
> 1. Coincidence
> 2. the antidepressants give them enough energy to commit suicide.

Both of these explanations are absolutely valid. However, I would appeal to you that you leave open your mind to the possibilities of a third, especially if you are in a position to influence the medical treatment of anyone suffering from depression.

By the way, statistics do demonstrate that antidepressants cause suicide. It is statistics that are fueling the whole uproar regarding the use of SSRIs in pediatrics. I am sure that the statistics are there for adults too. We just need an expert like you to look for them once the trial data becomes public.

On a more anecdotal note: The following drugs made my depression moderately - severely worse. Reboxetine and moclobemide in particular induced a suicidal state.

amoxapine
bupropion
donepezil
idazoxan
mirtazapine
moclobemide
protriptyline
reboxetine
triiodothyronine
valproate


Best wishes,

- Scott

 

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