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Re: Best Med for Motivation

Posted by Ktemene on July 9, 2004, at 23:23:19

In reply to Best Med for Motivation, posted by craig getty on July 7, 2004, at 12:31:59

> I was curious which meds people have had success with for raising their motivation. I'm currenly on Wellbutrin SR, but need to add something that will help me get excited about things and follow through with projects.
>
> I've tried Provigil, and although it keeps me awake, it doesn't give me motivation and actually makes me irritable.
>
> What has worked for you?

*Neuropsychiatry: An Introductory Approach* (by David Arciniegas and Thomas Beresford) has the following list of medicines used to treat diminished motivation and apathy:
Bromocriptine 2.5 mg TID – 20mg TID (+) dopamine
Levodopa/carbidopa 10/100 mg BID – 50/250 mg QID (+) dopamine
Pergolide 00.5-1.5TID (+) dopamine
Amatadine 50mgBID – 100mgTID (+) dopamine
Methylphenidate 2.5-20 TID (+) dopamine/norepinephrine
Dextroamphetamine 2.5-20mg TID (+) dopamine/norepinephrine
Buproprion 75-150BID (+) dopamine/norepinephrine
Selegiline 5-10mg QD (+) dopamine/phenylethylamine
Protriptyline 15-60 QD (+) norepinephine, (-)acetylcholine/histamine
Tacrine 40mg QD-40mgQID (+) acetylcholine
Donepezil 5-10QD (+) acetylcholine

I've tried Adderall, Selegiline and Buproprion (Wellbutrin), and I would say that all three are useful, but Adderall and Selegiline are more effective for motivation than Buproprion.


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