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Re: Xanax and GABA how does it work Buckeye Fan

Posted by chemist on May 26, 2004, at 21:38:15

In reply to Re: Xanax and GABA how does it work, posted by Buckeye Fan on May 25, 2004, at 7:54:27

> I appreciate the Info Chemist...could you explain further. I have always seen alprazolem listed as a Benzo.
>
> Whats the diffence?
>
> thanks
> Buckeye FAN

hello there, chemist here...i apologize for the delay, busy....xanax is a triazolobenzodiazepine, and is in the same class as estalopram and triazolam. tradiational benzos are 1,4 and 1,5 substituted drugs. xanax incorporates a triazolo group, making the binding affinity for the omega sub-site in GABA_{A} more pronounced. as one can taper from, say, valium to klonopin, one cannot with reasonable comfort taper from xanax to a 1,4 or 1,5 benzo...all the best, chemist


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