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Re: Mirapex or Abilify? Anyone tried both?

Posted by harryp on May 8, 2004, at 8:57:04

In reply to Mirapex or Abilify? Anyone tried both?, posted by rod on May 8, 2004, at 5:26:27

I'm a little confused. You're taking an antipsychotic (amilsulpride) now that is a dopamine antagonist (blocks dopamine receptors), yet are considering a drug (Mirapex) that is a dopamine agonist (activates dopamine receptors)! You would be taking two drugs with opposite effect, and the results would be hard to predict.

Abilify is a "partial agonist" of Dopamine, and supposedly "normalizes" dopamine levels--although I suspect in most cases it acts as an antagonist. Taking it along with amilsulpride also seems contradictory and unwise.

What symptoms are you trying to control?


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