Posted by Sad Panda on April 12, 2004, at 21:31:45
In reply to wierd reaction to remeron, posted by ravenstorm on April 12, 2004, at 20:35:58
> OK, why do I ALWAYS have to react to meds in such a wierd way!!!!!!!!!!
>
> I was awake/asleep/awake/asleep all night and for a portion of the night I was awake for quite some time. On remeron, for God's sake!!
>
> What is worse is my sleep had finally stabilized so I was sleeping through the night (although it was taking me 1-2 hours to fall asleep). SIGH.
>
> The good news is that I had lots of energy today. The bad news is that I had a lot of anxiety.
>
> Also, my "belly" (I'm 5'5", 115lbs) is protruding and pants that have been falling off of me from weight loss were snug around the middle. Have not gained weight, so it must be water retention. Don't really give a damn about this at the moment. Much more concerned about the sleep and anxiety.
>
> Can remeron make your anxiety worse before it gets better, or is this drug just going to be too activating for me?
>
> It would just be nice if I would react to something in the predictable fashion!
>
> OK, bitch-fest over. Sorry, sorry, sorry.
>
> P.S. Crazy-chick if you read this, I think acupuncture can actually be really helpful for a lot of things.
>
> Sad panda-I hear you about the natural stuff. Although, I have to say that the stuff the naturopath had me trying (5htp, l-tyrosine) I think works well for a lot of people, but I just couldn't take it on an empty stomach anymore and it just didn't have the same good effect when I took it with food. Also, I think the naturopath I went to was sort of irresponsible in that he told me that every person he had tried the products on had gotten better and then had a person with a weak stomach and GERD take the pills on an empty stomach.
>
> In fact, the reason I'm having to try remeron right now is because I couldn't take prozac due to stomach upset after the natural supplements, even though in the past I was able to use prozac with no problems (I took it while trying to get off paxil). SIGH
>
> Thanks again you guys for the support. I really appreciate it!
>
>What doseage did you actually end up taking? At low doses it solely blocks H1 receptors (anti-histamine), as the dosage increases it rapidly saturates these recptors(because it is the strongest antihistamine on the market) & then it overflows into the 5-HT2A, 5-HT2C & 5-HT3 receptors. These are good to block & are known to reverse SSRI induced side effects. At still higher doses it starts to block Alpha-2 NE recptor which can be stimulating, but for me the stimulation was causing me to be crank & irritable, it is most likely to be what is waking you up. It took me ages to tolerate 30mg & the only reason I increased from 15 to 30mg was for a further decrease in Effexor side effects. It also causes me fluid retention around the feet at 30mg, which I wasn't getting at 15mg.
Cheers,
Panda.
poster:Sad Panda
thread:334338
URL: http://www.dr-bob.org/babble/20040412/msgs/335741.html